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Proper dissolution of your sample is necessary for the experiment to begin. However, when faced with hydrophobic polypeptides, how to determine the optimal dissolution conditions will often take a lot of time, and the consumption of samples is inevitable. Excessive consumption may result in insufficient remaining polypeptide samples to complete your subsequent experiments. In addition, incomplete dissolution of peptides will lead to partial sample loss and inaccurate quantification, thus affecting the experimental data.

Chinapeptides(QYAOBIO) Dissolution test service can help you to deal with various properties of peptides more leisurely. You will not need to perform additional tests to estimate the solubility of the sample. We will provide you with a complete and customized report on the dissolubility of the peptide. You can also refer to the Guidelines for Dissolving to determine the most suitable solvent to dissolve the peptide to the appropriate concentration quickly.

Service content and delivery:
  • 1
    Evaluate the sequence characteristics of your polypeptide and customize the solubility measurement scheme
  • 2
    Analyze your peptide dissolution characteristics by several most common used solvents Systematically.
  • 3
    We will send the customized dissolubility test report to you for reference.
Test Specification Result
Dissolubility: 1mg/ml in PBS (pH=7.4±0.2) Insoluble
1mg/ml in H2O Insoluble
1mg/ml in 1%DMSO Insoluble
1mg/ml in 50%ACN/50%HCOOH Soluble

*We will try three common used solvents (PBS (pH 7.4 ± 0.2), pure water, and 1% DMSO) in sequence to do the dissolution test.. If there is no special requirement, we will only try them until they can be dissolved. The form of the report table depends on the peptide's own sequence and the dissolution test results within a certain range. The default peptide concentration is 1mg/ml. If you have special needs, you can try as required.

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